STUDI ETNOFARMAKOLOGI TUMBUHAN OBAT YANG DIGUNAKAN OLEH PENYEHAT TRADISIONAL UNTUK MENGATASI DIARE DI SULAWESI SELATAN
Abstract
ABSTRACT
Medicinal plants for health effort and diseases treatment has been used by ethnic groups in South Sulawesi for years. One of them is for diarrhea treatment. South Sulawesi is one of the top five provinces with the highest incidence and period prevalence of diarrhea in Indonesia. The purpose of this study was to investigate the species of medicinal plants used by traditional healer in South Sulawesi for anti-diarrhea and their scientific evidence. The data was obtained from the exploration of local ethnomedicin knowledge and medicinal plant based on community in Indonesia in 2012-2015 and 2017. The data was analyzed to find out the fidelity level, used value (UV), choice value (CV), and factor of informant’s consensus (FIc). The result reported information about thirty medicinal plants used for diarrhea treatment, including the plants name, part used, and preparation method that obtained from 48 traditional healer of 19 ethnic groups in South Sulawesi. The fidelity level were 41,67% for Psidium guajava, 8,33% for Mangifera sp, 6,25% for Curcuma domestica and C. Zedoaria, 4,17% for Allium cepa, Anacardium officinale, Syzigium cumini, and C.xanthorrhiza. The highest UV and CV were 0,42 and 13,84 for Psidium guajava. The informant’s consensus of medicinal plant for diarrhea treatment was 0,38. The commonly used parts was the leaves and most of the used methods were administered orally. The conclusions of this study were ethnic groups in South Sulawesi has various formula of medicinal plants for diarrhea treatment, but P.guajava was the most commonly used. Those formulas information for diarrhea treatment would be an alternative to overcome diarrhea problems in South Sulawesi.
Key words: medicinal plant, traditional healer, diarrhea,
ABSTRAK
Pengetahuan lokal dalam pemanfaatan tumbuhan obat untuk mencegah dan mengatasi penyakit telah dimiliki secara turun temurun oleh etnis-etnis di Sulawesi Selatan. Salah satunya adalah untuk mengatasi diare. Sulawesi Selatan termasuk dalam lima provinsi dengan insiden maupun period prevalence diare tertinggi di Indonesia. Tujuan dari penelitian ini adalah untuk mengungkap jenis-jenis tumbuhan obat yang digunakan hatttra di Sulawesi Selatan dalam ramuan anti diare dan bukti ilmiah penggunaan tanaman obat tersebut untuk mengatasi diare. Studi ini menggunakan data sekunder yang diperoleh dari Eksplorasi pengetahuan lokal etnomedisin dan tumbuhan obat berbasis komunitas di Indonesia pada tahun 2012,2015 dan 2017. Analisis data dilakukan untuk mengetahui Fidelity level, Used value, Choice value, Factor of informant’s consensus dan studi referensi ilmiahnya. Hasil studi menunjukkan informasi tentang tiga puluh tanaman obat untuk mengatasi diare yang diperoleh dari 48 penyehat tradisional yang berasal dari 19 etnis di Sulawesi Selatan. Informasi tersebut termasuk nama tanaman, bagian yang digunakan, dan metode persiapan. Fidelity level yang tertinggi adalah 41,67% untuk Psidium guajava, disusul 8,33% untuk Mangifera sp, 6,25% untuk Curcuma domestica dan C. Zedoaria, 4,17% untuk Allium cepa, Anacardium officinale, Syzigium cumini, dan C. xanthorrhiza. Nilai UV dan CV tertinggi adalah 0,42 dan 13,84 untuk P. guajava. Konsensus informan tentang tanaman obat untuk pengobatan diare adalah 0,38. Bagian yang umum digunakan adalah daun dan sebagian besar cara pemakaian dengan diminum. Dari hasil tersebut dapat disimpulkan bahwa kelompok etnis di Sulawesi Selatan memiliki berbagai formula tanaman obat untuk mengatasi diare, tetapi P.guajava adalah yang paling banyak digunakan. Informasi formula untuk mengatasi diare diharapkan dapat menjadi alternatif untuk masalah diare di Sulawesi Selatan.
Kata kunci: tumbuhan obat, penyehat tradisional, diare
References
DAFTAR PUSTAKA
Aeni, N., Purnama, A. A., & Afifah, N. (2017). Identifikasi tumbuhan obat di Kecamatan Kunto Darussalam Kabupaten Rokan Hulu. Jurnal Ilmiah Mahasiswa FKIP Prodi Biologi, 3(1), 1– 6.
Ajizah, A. (2018). Sensitivitas Salmonella typhimurium terhadap Ekstrak Daun Psidium guajava L. Bioscientiae, 1(1), 31–38.
Akpede, G. O., Igene, J. O., & Omotara, B. A. (2001). Perceptions of and Management Practices for Diarrhoeal Diseases by Traditional Healers in Northeastern Nigeria. Journal of Health, Population and Nutrition; London, 19(2), 91–9.
Aldini, R., Budriesi, R., Roda, G., Micucci, M., Ioan, P., D’Errico-Grigioni, A., Mazzella, G. (2012). Curcuma longa Extract Exerts a Myorelaxant Effect on the Ileum and Colon in a Mouse Experimental Colitis Model, Independent of the Anti-Inflammatory Effect. PLoS One; San Francisco, 7(9). http://dx.doi.org/10.1371/journal.pone.0044650
Alkizim, F., Matheka, D., & Muriithi, A. (2012). Dose-dependent myocardial toxicity of Mangifera indica during diarrhoea treatment. African Journal of Pharmacology and Therapeutics, 1, 67–70.
Alsarhan, A., Sultana, N., Al-Khatib, A., & Kadir, M. R. A. (2014). Review on Some Malaysian Traditional Medicinal Plants with Therapeutic Properties. Journal of Basic and Applied Sciences, 10(0), 149–159.
Anbuselvi, S., & Rebecca, J. (2017). Phytochemical Biochemical and Antimicrobial Activty of Psidium Guajava Leaf Extract. Journal of Pharmaceutical Sciences and Research; Cuddalore, 9(12), 2431–2433.
Araújo, T. S. L., Costa, D. S., Sousa, N. A., Souza, L. K. M., de Araújo, S., Oliveira, A. P., … Medeiros, J. V. R. (2015). Antidiarrheal activity of cashew GUM, a complex heteropolysaccharide extracted from exudate of Anacardium occidentale L. in rodents. Journal of Ethnopharmacology, 174, 299–307. https://doi.org/10.1016/j.jep.2015.08.020
Azam, G., Noman, S., & Pavel, A. M. (2017). Evaluation of anti-diarrhoeal activity of Curcuma zedoaria rhizome. Journal of Pharmacognosy and Phytochemistry, 6(3), 171–173.
Azam, M. G., Noman, M. S., & Al-Amin, M. M. (2014). Phytochemical Screening and Antipyretic Effect of Curcuma zedoaria Rosc. (Zingiberaceae) Rhizome. British Journal of Pharmaceutical Research, 4(5), 569–575.
Badan Litbangkes Kemenkes RI. (2013). Riset Kesehatan Dasar (RISKESDAS) 2013 (hlm. 47–48, 75–76, 306). Jakarta: Badan Litbangkes Kemenkes RI.
Badan Pusat Statistik Sulawesi Selatan. (2017). Provinsi Sulawesi Selatan dalam Angka 2107. Makassar: Badan Pusat Statistik Provinsi Sulawesi Selatan. Diambil dari https://sulsel.bps.go.id/publications
Biswas, B., Rogers, K., McLaughlin, F., Daniels, D., & Yadav, A. (2013). Antimicrobial Activities of Leaf Extracts of Guava (Psidium guajava L.) on Two Gram-Negative and Gram-Positive Bacteria. International Journal of Microbiology; New York, 2013, 1–7. http://dx.doi.org/10.1155/2013/746165
Daswani, P., Gholkar, M., & Birdi, T. (2017). Psidium guajava: A single plant for multiple health problems of rural Indian population. Pharmacognosy Reviews; Bangalore, 11(22), 167– 174. http://dx.doi.org/10.4103/phrev.phrev_17_17
Dicky, A., & Apriliana, E. (2016). Efek Pemberian Ekstrak Temulawak (Curcuma Xanthorrhiza Roxb) terhadap Daya Hambat Pertumbuhan Staphylococcus Aureus dan Escherichia Coli secara In Vitro. Jurnal Kedokteran Universitas Lampung, 1(2), 308–312.
Gazzaneo, R. S., Lucena, R., & Albuquerque, U. (2005). Knowledge and use of medicinal plants by local specialists in a region of Atlantic Forest in the state of Pernambuco (Northeastern
Brazil). Journal of Ethnobiology and Ethnomedicine, 1(9), 1–8. https://doi.org/10.1186/1746-4269-1-9 Gutiérrez, R. M. P., Mitchell, S., & Solis, R. V. (2008). Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology. Journal of Ethnopharmacology, 117(1), 1–27. https://doi.org/10.1016/j.jep.2008.01.025
Jaradat, N. A., Ayesh, O. I., & Anderson, C. (2016). Ethnopharmacological survey about medicinal plants utilized by herbalists and traditional practitioner healers for treatments of diarrhea in the West Bank/Palestine. Journal of Ethnopharmacology, 182, 57–66. https://doi.org/10.1016/j.jep.2016.02.013
Kumar, K. R., Shaik, A., Gopal, J. V., & Raveesha, P. (2013). Evaluation of antidiarrhoeal activity of aqueous bulb extract of Allium cepa against castor oil-induced diarrhoea. International Journal of Herbal Medicine, 1(3), 64–67.
Listyawati, S. (2006). Toxicity studies of the rhizome Curcuma xanthorrhiza Roxb. and Curcuma zedoaria Roscoe on hematological and male reproduction system of mice (Mus musculus L.). Biofarmasi Journal of Natural Product Biochemistry, 4(1), 10–13. https://doi.org/10.13057/biofar/f040103
Mada, S. B., Garba, A., Muhammad, A., & Mohammed, A. (2012). Phytochemical Screening and Antimicrobial Efficacy of Aqueous and Methanolic Extract of Mangifera indica (Mango Stem Bark). World Journal of Life Sciences and Medical Research, 2(2), 81. Maroyi, A. (2013).
Traditional use of medicinal plants in south-central Zimbabwe: review and perspectives. Journal of Ethnobiology and Ethnomedicine; London, 9(31), 1–18. http://dx.doi.org/10.1186/1746-4269-9-31
Micucci, M., Aldini, R., Cevenini, M., Colliva, C., Spinozzi, S., Roda, G., … Budriesi, R. (2013). Curcuma longa L. as a Therapeutic Agent in Intestinal Motility Disorders. 2: Safety Profile in Mouse. PLoS One; San Francisco, 8(11), 1–14. http://dx.doi.org/10.1371/journal.pone.0080925
Morais-Braga, M. F. B., Carneiro, J. N. P., Machado, A. J. T., dos Santos, A. T. L., Sales, D. L., Lima, L. F., … Coutinho, H. D. M. (2016). Psidium guajava L., from ethnobiology to scientific evaluation: Elucidating bioactivity against pathogenic microorganisms. Journal of Ethnopharmacology, 194, 1140–1152. https://doi.org/10.1016/j.jep.2016.11.017 Noorhidayah, N. (2006).
Potensi dan Keanekaragaman Tumbuhan obat di Hutan Kalimantan dan Upaya Konservasinya. Jurnal Analisis Kebijakan Kehutanan, 3, 95–107. https://doi.org/10.20886/jakk.2006.3.2.95-107
Ojewole, J. A. O., Awe, E. O., & Chiwororo, W. D. H. (2008). Antidiarrhoeal activity of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rodents. Journal of Smooth Muscle Research, 44(6), 195–207. https://doi.org/10.1540/jsmr.44.195 Ojezele,
Obaineh, M., & Shadrach, A. (2013). Phytochemical Constituents and Medicinal Properties of Different Extracts of Anacardium Occidentale and Psidium Guajava. Asian Journal of Biomedical dan Pharmaceutical Sciences, 3(16), 20–23.
Okonkwo, T. J. N., Okorie, O., Okonta, J. M., & Okonkwo, C. J. (2010). Sub-chronic Hepatotoxicity of Anacardium occidentale (Anacardiaceae) Inner Stem Bark Extract in Rats. Indian Journal of Pharmaceutical Sciences, 72(3), 353–357. https://doi.org/10.4103/0250-474X.70482
Olajuyigbe, O. O., & Afolayan, A. J. (2012). Ethnobotanical survey of medicinal plants used in the treatment of gastrointestinal disorders in the Eastern Cape Province, South Africa. Journal of Medicinal Plants Research, 6(18), 3415–3424. https://doi.org/10.5897/JMPR11.1707
Omoboyowa, D., C Fred, O., Elijah Nwodo, P., & Joshua, P. (2013). Anti-diarrhoeal activity of chloroform-ethanol extracts of Cashew (Anacardium occidentale) kernel. Journal of Natural Products, 6, 109–117.
Owolabi, O. J., Arhewoh, M. I., & Aadum, E. J. (2012). Evaluation of the Antidiarrhoeal Activity of the Aqueous Rhizome Extract of Curcuma Longa. Journal of Pharmaceutical and Allied Sciences, 9(1), 1450–1457.
Pan, S.-Y., Litscher, G., Gao, S.-H., Zhou, S.-F., Yu, Z.-L., Chen, H.-Q., … Ko, K.-M. (2014). Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources. Evidence-Based Complementary and Alternative Medicine, 2014, 1–20. https://doi.org/10.1155/2014/525340
Sabale, P., Modi, A., & Sabale, V. (2013). Curcuma longa Linn. A Phytochemical and Phytopharmacological Review. Research Journal of Pharmacognosy and Phytochemistry; Raipur, 5(2), 59–68.
Salgado, H., Ronchari, A., Michelin, D., & Moreira, R. (2006). Evaluation of antidiarrhoeal effects of Psidium guajava L. (Myrtaceae) aqueous leaf extract in mice. Journal of Basic and Applied Pharmaceutical Sciences, 27(1), 89–92.
Sari, N., Wahidah, B. F., & Gaffar, N. A. (2017). Etnobotani Tumbuhan yang Digunakan Dalam Pengobatan Tradisional di Kecamatan Sinjai Selatan Kabupaten Sinjai Sulawesi Selatan. Prosiding Seminar Nasional Biology for Life, 6–13.
Sa’roni, Winarno, W., Adjirni, & Pudjiiastuti. (2011). Profil Pengobat Tradisional Ramuan dan Ramuan Obat Herbal yang digunakan di Sulawesi Utara, Kalimantan Selatan dan Lam. Media Penelitian dan Pengembangan Kesehatan, 21(2), 71–81. https://doi.org/10.22435/mpk.v21i2 Jun.107.
Setyowati, F. M. (2010). ETNOFARMAKOLOGI DAN PEMAKAIAN TANAMAN OBAT SUKU DAYAK TUNJUNG DI KALIMANTAN TIMUR. Media Litbang Kesehatan., 20(3), 104–112.
Shad, A. A., Ahmad, S., Ullah, R., AbdEl-Salam, N. M., Fouad, H., Rehman, N. U., Saeed, W. (2014). Phytochemical and Biological Activities of Four Wild Medicinal Plants. The Scientific World Journal; Cairo, 2014, 1–7. http://dx.doi.org/10.1155/2014/857363
Shakir, B., Shakir, S., Hussein, N., & Habeeb, K. (2018). Antimicrobial Activity Of Allium Cepa Extracts against Aeromonashydrophila Isolated From Diarrhea Samples Of Children in Iraq. International Journal of Advanced Research, 6(6), 63–70. https://doi.org/10.21474/IJAR01/7188
Silalahi, M. (2017). Curcuma xanthorrhiza Roxb (Pemanfaatan dan Bioaktivitasnya. Jurnal Dinamika Pendidikan, 10(3), 248–260.
Silva, S., Abreu, I., Fernanda C. Silva, G., M. Ribeiro, R., de S. Lopes, A., Cartágenes, M., … Borges, M. (2012). The toxicity evaluation of Syzygium cumini leaves in rodents. Revista Brasileira de Farmacognosia, 22. https://doi.org/10.1590/S0102-695X2011005000181
Srivastava, S., & Chandra, D. (2013). Pharmacological potentials of Syzygium cumini: a review. Journal of the Science of Food and Agriculture, 93(9), 2084–2093. https://doi.org/10.1002/jsfa.6111
Suparman, S., Diniatik, D., Kusumaningrum, Y., & Yulianto, Y. (2012). Studi Etnobotani Tumbuhan Sub Kelas Rosidae dan Penggunaannya sebagai Obat Tradisional di Kecamatan Baturraden Kabupaten Banyumas. Sainteks, 8(2), 1–8.
Thomas, B. T., Soladoye, M. O., Adegboyega, T. T., Agu, G. C., & Popoola, O. D. (2015). Antibacterial and Anti-Inflammatory Activities of Anacardium occidentale Leaves and Bark Extracts. Nigerian Journal of Basic and Applied Sciences, 23(1), 1–6.
Udomthanadech, K., Vajrodaya, S., & Paisooksantivatana, Y. (2015). Antibacterial Properties of the Extracts from Some Zingibereous Species in Thailand against Bacteria Causing Diarrhea and Food Poisoning in Human. International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 6(5), 203–212. https://doi.org/0.14456/itjemast.2015.4
Wadkar, KA, Magdum,CS, Patil, SS, & Naikwade. (2008). Anti-diabetic Potential and Indian Medicinal Plant. Journal of Herbal Medicine and Toxicology, 2(1), 45–50. WHO. (2017). Diarrhoeal disease. Diambil dari http://www.who.int/news-room/factsheets/detail/diarrhoeal-disease
Yusuf, S., Mohammed, A., & Ndanusa, R. (2009). Effect of aqueous extract of Anacardium occidentale (L) stem bark on sodium and chloride transport in the rabbit colon. Journal of Medicinal Plants Research, 3(6), 493–497.
